Epidemiological Studies

Expand beyond simple yet expensive RCTs to use a full spectrum of research methods that can meet your goals.

A full range of research tools

Epidemiological studies evaluate the factors that lead to disease and other negative health outcomes. When you need to substantiate safety of your product for a new target market, to protect against claims, or for other strategies, clinical trials are neither the most cost effective nor scientifically valid studies for this purpose. Epidemiological research studies, such as case-control, retrospective or prospective cohort, cross-sectional, and ecological studies offer a cost effective approach that can confirm your product’s safety in relation to specific health outcomes.

Epidemiological studies may also be required as evidence for an IND or NDA application or to substantiate FTC claims. These studies provide valuable evidence regarding your product’s mechanisms of action, safety, potential clinical efficacy, and relationship to health outcomes in large communities. These studies can also help to identify potential avenues for further research you have not yet considered.

Epidemiological Research Services Include

Case Control Studies

Need to investigate claims about a risk associated with a product ingredient? Are you an ingredient supplier in need of substantiation about your ingredient's safety?

Case control studies offer a safe, ethical way to evaluate risk among users of your products. If your product or ingredient is suspected of causing adverse health effects, case-control studies allow you to scientifically substantiate your product's safety.

Cross Sectional Studies

Cross-sectional studies offer a snapshot of the environment. These can be used to demonstrate the absence of a relationship between ingredients or products and health outcomes.

They can also be used to learn more about the type of people using your products and what health conditions they are addressing.

Cohort Studies

Our team conducts both prospective and retrospective cohort studies, allowing you to study the health needs and outcomes associated with us of your products or brand as a whole. Depending on the commonality of your product/ingredient and suspected health risks, retrospective cohort studies may be more appropriate for confirming safety than case-control studies.

Prospective cohort studies are also useful for assessing needs and outcomes among your target population or among your product or ingredient's consumers.

Meta Analysis

A meta analysis is a systematic way to quantify the total effect size of an ingredient or product and to control for variables that may moderate that effect. Practically, this means the meta analytic methodology is able to produce a more generalizable effect of your product or ingredient across a wide range of markets. The research is also able to identify ways in which the total effect of your product or ingredient may be altered–both positively and negatively.

A meta analysis can:

  • Provide clarity when published studies have conflicting results, allowing you to substantiate structure / function claims without the cost of larger studies
  • Identify populations, health conditions, or other factors that play a role in moderating your product's efficacy
  • Resolve consumer confusion created by click-bait media headlines by establishing the strongest level of causal evidence
  • Increase your product/ingredient’s scientific validation

Our team is highly skilled in conducting meta analyses and is among the most widely published researchers using this methodology in the natural products market.

Why is this critical? Many natural product clinical trials are underpowered, reflect poor methodology, and use subclinical dosing. A meta analysis can correct for these factors, cutting through the noise, and identifying the true potential of your product.

Meta analysis does not require ethics authorizations or trial registries, and they can be completed in as little as 4-6 weeks.

Studies for your unique needs

Our team can offer insight as to the suitability of epidemiological studies for your unique needs. We can also develop research protocols and conduct these studies for your company.